inkycircus

Who you gonna call - Johns Hopkins

FRUIT FLY CELLS / GREEN THING FROM GHOSTBUSTERS MIGRATING ACROSS AN EGG.

What is it that makes cancer cells migrate from the main site of growth to other healthy tissues and how exactly do they move? A professor of Biological Chemistry at Johns Hopkins called Denise Montell (along with her team) have just brought us one step closer to finding out, and made a nifty video in the process.

In a impressive display of patience, Dr Montell and her team spent a year feeding a cluster of fruit fly cells inside an egg chamber with different solutions, trying to find the right one that would make the cluster migrate from one side of the egg to the other. These fruit fly cells are not cancerous, but what they are doing resembles what the cancer cells do and how they move. However, you can't watch them moving inside the ovary but if you take them out of the ovary they refuse to budge. Hence the need for the ideal medium to get them going. When the team finally hit on the perfect formula, they made a video, and you can now watch that process of cell migration online. You can see from video that different cells seem to take the lead in propelling the cluster forward at any one time, a movement compared to a flock of geese or a pack of cyclists. The team have also discovered a key protein that encourages this movement, called Kuzbanian. This will all translate to a better understanding of clinically useful cell migrations as well as cancer cell migrations.

One final thing, is there not an eerie similarity between the migrating cells and that green thing from Ghostbusters?

Newsflash - London not so filthy after all!

It's official! London really isn't that dirty anymore! Well, the wetlands around Greater London aren't anyway. Squacco herons haven't been seen in the vicinity of my home town for a century and a half, but one was spotted in Crossness Nature Reserve in Bexley on the 29th of May. More importantly, the bird didn't take one sniff of the local sights and hotfoot it home again, it's been there ever since. The nature reserve has recently spend a hefty wedge on regenerating their wildlife zones, so they're understandably delighted.

The heron was last seen in London in 1866. For a little historical perspective, that was the middle of Queen Victoria's reign, the year after Abraham Lincoln died, and the year (according to wikipedia) that Darwin decided to grow his fantastic world-beating beard. 1866 was also the year the urinal was patented, the year that the Canadian Parliament met for the first time, and the year that root beer and dynamite were invented. But all of those events are frankly boring compared to the last known sighting of a squacco heron in north west London. So the arrival of one of these small beige birds (it's London, of course the bird would be beige, no hot pink flamingoes for us) after such a long time is big news for British twitchers (and anyone who cares about a nice clean environment).

Via BBC News.

Salad dressing face mask to the rescue

'Restoring' priceless works of art has never been an easy task. While it might have seemed like a good idea back in the 1960s to cover the porous marble of Michelangelo's David (and plenty of other valuable frescoes) in an acrylic polymer called paraloid, now it just seems downright insane. But how do you get the toxic coating off once you've plastered it on? Not with a nail brushes that's for sure. So step up the face mask.

A team from the University of Florence have discovered a way to make oil and water mix, by using a sugar-like molecule to emulsify them. Like a nanoparticle salad dressing without the vinegar. Or mustard. Anyway, the artwork is draped in thin Japanese paper and then the 'dressing' is poured on. This poultice is left on for a couple of hours and hey presto, no more paraloid. This technique only works where the slap happy sixties restorers plastered their paraloid, it's no help where other damage has been done in the name of restoration. But for David and his compatriots, it's good news indeed.

Via ABC News Australia. (PHOTO: NZRIC)

Chatty paper

CAN SPEAKING PAPER FIGURE OUT A WAY TO MAKE MONEY LITERALLY TALK? (PHOTO: MANJIDES)

A team from Mid Sweden University have produced a prototype billboard embedded with conductive inks and printed speakers, so that when you touch it it plays audio at you. The article in BBC News says that the inventors think it could be useful in product packaging - and I do see the temptation. However, I don't really need my yoghurt to tell me how many grammes of fat it has or exactly how tasty it is. That would cause quite the cacophony in supermarkets.

Seems to me that this would be more useful for blind people, as a high-tech version of braille. But there'd presumably have to be some way of listening privately though (a printed headphone jack perhaps), otherwise you could reach the end of your intellectual magazine only to find it suddenly starts shouting out all the adverts for sex phone lines that are printed at the back. Very embarrassing.

As light as a geological hammer

A little bit of magic for a drizzly Monday morning (unless of course it's sunny everywhere but Britain...) comes to you courtesy of NASA.com and features a phenomenon called the equivalence principle. Back in the 16th century, Galileo Galilei rolled spheres made of different materials down a long slope, and showed that even though the spheres were very different, they reached the bottom of the slope at the same time. He concluded that gravity accelerates all objects equally regardless of their masses or the materials from which they are made. This 36 year old video shows astronaut David Scott, demonstrating just that, by standing on the moon and dropping a heavy geological hammer and a light falcon feather. Both items hit the ground at the same time, reinforcing Galileo's theory.

The experiment shown in the above video isn't necessarily the most accurate scientific demonstration (nor is it brilliant quality, unsurprisingly), but it was the first such demonstration to be done on the moon, and it's very eye-catching. Even though you know the outcome, it's just impossible to make your brain accept that the hammer and the feather will fall at the same rate. And yet they do.

How to avoid being lunch

THE STUDY ISN'T ABOUT ATLAS MOTHS BUT I COULDN'T RESIST THE PIC. (PHOTO: TRIJNE)

In the good ole natural selection race, he who adapts best survives. Take for example a butterfly's fancy wing spots that are meant to look like scary eyes. It's a clever tactic. Moths have evolved a similarly cunning method of evading capture and certain death, which was reported in the Proceedings of the National Academy of Sciences this week.

Some moths make noises and some don't, but doctoral student Jesse Barber from Wake Forest University has noticed that there is more of a motive than mere musicality to the moth's sounds. Bats eat moths, and prefer the taste of some to others. This study used three types of moth, two nice-tasting, and one nasty-tasting, and offered them to bats. The unappetizing moths made noises as they flew, and the bats soon learned that noise=yuk. So when offered a selection of more delicious moths the bats avoided the noisy ones and scoffed the silent ones. The tasty, noisy moths live to flutter another day, and descent with modification marches on. Go Darwin.

In space no-one can hear you scream

We depend on the Sun for life, but it an unpredictable master. Every now and again it flings out bundles of joy known as Coronal Mass Ejections (CMEs), which can do an awful lot of damage when they slam into our vulnerable little planet. The CMEs can produce magnetic storms that could have the power to knock our gadget-heavy lifestyle back into the dark ages. Most of the CMEs aren't anything like that powerful, in fact they happen reasonably often and usually don't do that damage. But they can do some damage, including messing with our satellites and electrical transmission lines. Which is why it's interesting news that a team at SOHO (The Solar and Heloispheric Observatory) have discovered that the really big ones are preceded by radio 'screams' from the Sun. Here's how it works:

Strong CME shocks accelerate electrons in the solar wind, which in turn produce the radio signal. The same strong shock must also accelerate atomic nuclei in the solar wind, which produce the radiation storm.

The radio signal moves at the speed of light, but the particles lag behind. So we can 'hear' the scream and know that the CME isn't far behind. The article from the European Space Agency explains how the early warning system could be helpful (and has a nice clear explanation of the phenomenon) - if astronauts are showboating around on the outside of spacecrafts they could be told to get inside rightaway to be protected from the extra radiation. Handy indeed. But seeing as how the Sun is quite big and we are quite small, if a big ejection is on the way it's not like we can say 'Umbrellas up! CME a-coming' just yet...

PHOTO: ETAC

My great-aunt was a shark you know

I CAN DEFINITELY SEE THE FAMILY RESEMBLANCE... (PHOTO:NATASHAW)
I was on a trip in South America once, and was trying to spell my name to a ticket agent to buy a bus ticket. The poor woman got a bit confused in the hustle and bustle, and got my name wrong, writing down "Katie Jaws" on my ticket. Turns out she was prescient, because I am related to sharks. Well, according to ABC News Australia we all are actually.

Long ago in the ancient mists of time (450 million years ago to be exact), we shared a relative with our toothy friends. The elephant shark has some genes that are nearly identical to ours, meaning we have more in common with it than we do with other species closer to us on the evolutionary tree. We also have genes in common with mice and dogs, but that's not so suprising since we're all mammals. But we do have at least two things in common with sharks, so it does make sense these traits or characteristics would be expressed in our genes. For one, a shark's immune system is similar to ours, as sharks have all four types of white blood cells that humans have. The other thing we have in common with sharks is sex. Fish that should be closer to us on the evolutionary tree abstain from sex, preferring to keep fertilisation tidily outside the body. Sharks don't do this, and in case you hadn't noticed, neither do we.

Fiddling with the food chain

Is is ok to kill a shark to save a seal? Not an easy decision to make. The National Oceanic and Atmospheric Administration thinks it's ok, and is currently seeking permission from the U.S. Fish and Wildlife Service and the state Department of Land and Natural Resources to kill 10 sharks in the coming year. The seal in question is the Hawaiian Monk Seal, and the shark is the Galapagos Shark.

The justification for the plan is that the monk seal is classified as endangered (IUCN - Hawaiian Monk Seals) and the sharks are not. They've asked for and got permission to do this before, so they clearly think it's a good way to protect the few seals that are left.

The sharks don't give an arse for the IUCN red list, or the fact that we meddlesome humans think that Monk Seals are cute and worthy of protection. We see an endangered species, they see lunch. Protecting endangered species is never a straightforward task, because the animals are never killed 'just because'. If a poacher has killed an elephant, he's not done it just to be mean. He's done it because the ivory is obscenely valuable and he can make a large amount of money from it. If we stop him, his livelihood is gone. And in stepping in to protect a disappearing species, you sometimes have to take extreme steps, like sacrificing one group of animals for another.

However, the shark is classified as near-threatened (IUCN - Galapagos Shark) meaning it is not vulnerable now but is likely to be in the near future. I would therefore hope that anyone making decisions like this has the mantra Beware The Cane Toad echoing their heads the whole time as an example of when we can get it wrong. We as a species do not have a particularly good track record in meddling with the natural world. But with that in mind, it is possible to get it right, and hopefully the NOAA will manage to do just that for the seals.

(PHOTO: PKEMP)

Lock up your scooters

 There's an orangutan on the loose. Mopeds in a Taiwan zoo faced a grizzly fate when a 150kg beast escaped from his cage and went on the rampage. The animal got a brief taste of freedom before the zoo keepers faced him with "weapons and shields", tranquilised him and returned him to his cage. The video of the great escapee (complete with truly spectacular orange fringed fur) can be found at BBC News, or, with less commentary but available to viewers across the pond, at local news station wkyc.com. Fringe or no fringe, he can stay away from my scooter thank you very much...

ONE DAY SOON, FREEDOM SHALL BE MINE. MWA HA HA. (PHOTO: IMAGE00139)